Mitochondrial Genome Editing Field Rapidly Expanding
International Journal of Molecular Sciences
New Advances in Molecular Research on Impaired Mitochondrial Metabolism in Disease
Mitochondrial Base Editing: Recent Advances towards Therapeutic Opportunities
National Library of Medicine
An optimized FusX assembly-based technique to introduce mitochondrial TC-to-TT variations in human cell lines
The FusX TALE Based Editor (FusXTBE) is a programmable base editing platform that can introduce specific TC-to-TT variations in the mitochondrial DNA (mtDNA).
Efficient multitool/multiplex gene engineering with TALE-BE
TALE base editors are a recent addition to the genome editing toolbox. These molecular tools are fusions of a transcription activator-like effector domain (TALE), split-DddA deaminase halves, and an uracil glycosylase inhibitor (UGI) that have the distinct ability to directly edit double strand DNA, converting a cytosine (C) to a thymine (T).